Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Laryngospasm
ADR ID BADD_A02487
ADR Hierarchy
22      Respiratory, thoracic and mediastinal disorders
22.04      Upper respiratory tract disorders (excl infections)
22.04.02      Laryngeal spasm, oedema and obstruction
22.04.02.002      Laryngospasm
Description A disorder characterized by paroxysmal spasmodic muscular contraction of the vocal cords. [CTCAE] A disorder in which the adductor muscles of the VOCAL CORDS exhibit increased activity leading to laryngeal spasm. Laryngismus causes closure of the VOCAL FOLDS and airflow obstruction during inspiration. [MeSH]
MedDRA Code 10023891
MeSH ID D007826; D007826; D007826
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Glottic spasm | Laryngeal spasm | Laryngismus | Laryngospasm | Larynx muscle hypersensitive | Spasm glottis | Spasm larynx | Laryngospasms | Laryngeal Spasm | Laryngeal Spasms | Spasm, Laryngeal | Spasms, Laryngeal
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00504Clopidogrel0.000736%
BADD_D00564Dabigatran etexilate--
BADD_D00603Delavirdine--
BADD_D00604Delavirdine mesylate--
BADD_D00611Desflurane--
BADD_D00629Dexmedetomidine0.001505%
BADD_D00648Diazepam--
BADD_D00657Dicloxacillin--
BADD_D00658Dicloxacillin sodium--
BADD_D00692Dipyridamole--
BADD_D00699Docetaxel0.000533%
BADD_D00716Doxapram--
BADD_D00717Doxapram hydrochloride--
BADD_D00731Droperidol--
BADD_D00747Edrophonium--
BADD_D00748Edrophonium chloride--
BADD_D00851Etomidate--
BADD_D00853Etophos--
BADD_D00854Etoposide--
BADD_D00855Etoposide phosphate--
BADD_D00879Fentanyl--
BADD_D00880Fentanyl citrate--
BADD_D00902Flecainide--
BADD_D00931Fluorouracil0.002352%
BADD_D00950Fluvoxamine--
BADD_D00951Fluvoxamine maleate--
BADD_D00952Folic acid0.000235%
BADD_D00978Fulvestrant0.003677%
BADD_D00983Gadobenate dimeglumine--
BADD_D00989Gadolinium--
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